Secretion of Atrial Natriuretic Peptide (Anp), Heart Reconditioning and Remolding in Elite Endurance Trained Athletes

Aim / Objective: The aim of this study was to evaluate the effect maximal exercise on level cardiac remolding and Atrial Natriuretic Peptide (ANP) in elite athletes as compared sedentary healthy subjects correlation ANP with adaptation athlete’s heart remodeling (if any) Place Duration Study: present carried out at Department Physiology, Army Medical College, collaboration Armed Forces Institute Cardiology (AFIC) Rawalpindi from June 2003 May 2004. Methodology: A total number 44 were included study. These comprised 22 endurance volunteers controls. All examined clinically rule cardiovascular pulmonary diseases basis medical history, physical examination, echocardiography. selected a Toshiba Power Vision 6000 echocardiograph for assessing measuring their LV end-diastolic internal diameter (LVIDd), Diastolic interventricular septal thickness (IVSTd), diastolic posterior wall (PWTd). left ventricular mass (LVM) calculated by using Devereux formula. They subject go ergometer cycle before breakfast. Blood samples drawn after assess samples. Results: It found that LVIDd, IVSTd, PWTd, LVM higher age, sex BMI matched levels plasma also high post pre sample Conclusion: Systolic blood pressure, Pressure rate are lower than Exercise increases significantly There Positive correlations between while there negative rate, pressure. However, none be statistically significant. Keywords: Athlete’s Heart, ANP, Cardiac athletes, Echocardiography